World Congress on Bioorganic and Medicinal Chemistry: Chemistry Involved in the Development of Bio-active Natural Products:

Most of the new entities have been generated from natural products (secondary metabolites) and from compounds derived from natural products. Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in developing new medicinal agents. And are often more efficient than man-made compounds if a specific biological activity is needed.

E.g.: As an enzyme inhibitor or as a toxin to kill a cancer cell.

Latest findings report and outline of their future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry. These studies mainly aimed at natural products chemists, medicinal chemists, Analytical Chemists, pharmacologists, as well as the pharmaceutical industries. From the past 20 years, pharmaceutical industries research step into the development of bioactive molecules from natural products and produce an emphasis on high-throughput screening of synthetic libraries and lead molecules. Currently, there is a substantial decline in new drug approvals and the impending loss of patent protection and compliance. For important medicines. However, Chemical and biological resources, smart screening methods, robotic separation with structural analysis, metabolic engineering, and synthetic chemistry offer exciting technologies for new natural product drug discovery and development. Advances in rapid genetic sequencing, coupled with manipulation of biosynthetic pathways, may provide a large resource for the future discovery of pharmaceutical agents.

Key features in the development of bioactive molecules from natural sources:

It deals with the synthesis, semi-synthesis, and biosynthesis of potentially bioactive natural products.
Bioorganic Chemistry advances in naturally occurring organic compounds describing their biochemical and biological transformations, mechanism of action of actions, and structure-activity relationships (SAR) studies.
50 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of bioorganic chemistry.